We develop the technology to detect tumors at an
early stage and achieve greater survival rates against cancer.

We develop the technology to detect tumors at an early stage and achieve greater survival rates against cancer.

Who we are

We are a team of scientists that have been studying extracellular RNA molecules for 15 years,
looking at new directions while thinking out-of-the-box.
We dream in a world where all cancers are detected at such an early stage that
the disease is no longer a big health concern.

What we do

B4-RNA aims to increase cancer survival by detecting tumors at a very early stage, before they grow and spread. To do this, we study RNA molecules released by cancer cells into the blood, rather than looking for the tumor itself.

We seek to achieve early cancer detection by means of a simple blood test that can be performed routinely in apparently healthy people.

How we do it

Cancer cells and healthy cells do not express the same amounts of RNA molecules, so sequencing RNAs in the blood can inform about the presence of an early tumor.

The problem is that RNA is rapidly degraded by a family of enzymes known as RNases, making it a very unstable molecule to study.

Our research team has discovered a family of RNA molecules that are stable in the bloodstream, making them perfect candidates for early disease detection.

These stable RNAs are invisible to conventional sequencing methods.

We have developed a proprietary sequencing method that can capture the whole set of RNA molecules circulating in the blood, with the help of artificial intelligence.

Our technology

Step 1

Collect a
blood sample

Step 2

Sequence the collected sample using our RNA extraction and repair method and a low-cost NGS sequencer.*

Step 3

Upload the sequencing data to our online platform

Step 4

Receive a report with the diagnostic results

* This can be performed by any healthcare provider with la facilities as our method is based on relatively abundant circulating RNAs. Hence, high sequencing depth is not required.